Name: AFB Susceptibility Add on Testing
Test Name: AFB Susceptibility Add on Testing
Health Link Test Code: HCAFBADD
LIS Test Code: AFBADD
This test is available only as an add-on request and an add-on order for AFB Susceptibility Add on Testing [HCAFBADD] must be placed in Health Link.
Add on testing is only available to a positive Mycobacteria culture.
1) To determine the in vitro susceptibility of M. tuberculosis complex organisms to first line antimicrobial agents, select 'AFB 1st Line Drugs' from the lists of tests to add on. Also note: Second line drugs will be tested on all M. tuberculosis complex organisms showing resistance to rifampin or multiple first line drugs.
2) To determine the in vitro minimum inhibitory concentration for clinically significant Rapid Growing Mycobacteria species select 'AFB Rapid Grower' from the list of tests to add on.
3) When a slow-growing non-tuberculosis mycobacteria or M. avium complex isolate has been recovered on culture you may add on the 'AFB, 10 Drug Panel' to National Jewish Lab.
4) Clarithromycin testing should be performed on isolates from blood or tissue (disseminated disease) and clinically significant respiratory specimens from patients who have failed prior macrolide therapy or prophylaxis. (MAC strains not previously exposed to macrolide therapy or prophylaxis are uniformly susceptible to the macrolides.) If this is desired, select 'MAC Susceptbilities/Clarithromycin' from the list of tests to add on.
Any additional testing should be determined by a consultation with the WSLH Mycobacteriology Lab.