Apr 5, 2015




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FISH- MDS Panel (HCSLHMDS) WSLH Cytogenetics Lab Test

Name: FISH- MDS Panel

Test Name: FISH- MDS Panel

Health Link Test Code: HCSLHMDS


CPT Code(s): 88271 x6, 88275 x4

Test Component:

870F44- Deletion 20q, FISH, D20S108

870F45- Deletion 5q31, Monosomy 5, FISH, EGR1

870F42- Deletion 7q31, Monosomy 7, FISH, D7S522

870F41- Trisomy 8, FISH, D8Z2


Look up individual test codes for more information.

Methodology: Fluorescence In Situ Hybridization (FISH)

Clinical Information:

Aids in diagnosis of hematologic disorders and for monitoring disease after treatment or bone marrow transplant.

Testing Site: Testing will be sent to an approved reference laboratory

Link: http://www.slh.wisc.edu/wslhApps/RefMan/wslhSearch.php

Days Performed: Mon-Sat.

In-Lab Turnaround Time: 3 - 5 days.

Specimen: Blood or bone marrow

Collection Container: Green top (with sodium heparin anticoagulant)

Collection Instructions:

Blood or bone marrow must be received and processed by WSLH within 24 hours of collection. Specimen must be received in UWHC Hospital Laboratory on Monday-Friday only.

Collection Volume: 2-3 mL blood or 0.5-1.0 mL bone marrow

Stability Ambient:

24 hours

Stability Refridgerated:

Not acceptable

Stability Frozen:

Not acceptable

Sample Analyzed: Whole Blood or Bone Marrow

Specimen Transport:

Transport specimen to UWHC Hospital Laboratory at room temperature. Transport with coolant pack during hot weather (>85°F).

Unacceptable Criteria:

Bone marrow/blood that is clotted or hemolyzed.


Interpretation provided with results.

Test Limitations:

Failure to identify an abnormal clone by FISH does not rule out the presence of other abnormalities in the specimen.

Additional Information:

If FISH assay is not performed in conjunction with chromosome analysis there is an additional charge for processing the specimen.