Test Name: Gabapentin
Health Link Test Code: HCGABA
LIS Test Code: GABA
CPT Code(s): 80171
Methodology: Liquid Chromatography
Days Performed: Mon-Fri, dayshift.
In-Lab Turnaround Time: 2 days.
Collection Container: Red top
Collect specimen for trough level prior to next dose.
Collection Volume: 2 mL
Pediatric Collection Volume: 1.5 mL
Sample Analyzed: Serum
Testing Volume: 1 mL
Pediatric Testing Volume: 0.5 mL
Centrifuge. Transfer cell-free serum to plastic vial. Refrigerate.
Transport specimen to laboratory. Transport with coolant pack if coming from clinic location.
Specimens collected in red cap with yellow ring (SST) tubes are not acceptable.
Definitive therapeutic concentration for gabapentin has not been established. A serum concentration of 5.0-15.0 mcg/mL is generally considered to be therapeutic for individuals 18 years old and up. Steady-state concentrations are nearly proportional to dose with maximum levels in the ranges of 3.0-5.0 mcg/mL, 4.4- 6.6 mcg/mL, and 6.0-11.0 mcg/mL, respectively, for doses of 300, 400 and 600 mg three times daily. Trough levels range from 1-10 mcg/mL at doses of 300, 400 and 600 mg three times daily.
Interpretation Type: Interpretive Guidelines
Result of "BELOW DETECTION" indicates that the result is below the method detection limit of 0.1 mcg/mL.
This test was developed and its performance characteristics determined by the UWHC Clinical Laboratories. This test meets the standards for clinical testing. This test should not be regarded as investigational or for research use. The US Food and Drug Administration (FDA) has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.