Test Name: Lidocaine
Health Link Test Code: HCLIDO
LIS Test Code: LIDO
CPT Code(s): 80176
Lidocaine and monoethylglycinexylidide (MEGX)
Methodology: Gas Chromatography
Antiarrhythmic, local anesthetic
Days Performed: Daily, dayshift- Pathology Resident approval is required after hours.
In-Lab Turnaround Time: 1 day.
Stat In-Lab Turnaround Time: 3 hours.
Collection Container: Red top
1) if lidocaine toxicity is suspected
2) whenever ventricular dysrhythmias occur despite lidocaine administration.
Collection Volume: 4 mL
Pediatric Collection Volume: 3 mL
Sample Analyzed: Serum
Testing Volume: 2 mL
Pediatric Testing Volume: 1 mL
Centrifuge. Transfer cell-free serum to plastic vial. Refrigerate.
Transport specimen to laboratory. Transport with coolant pack if coming from clinic location.
Specimens collected in red cap with yellow ring (SST) tubes are not acceptable.
|Generally effective therapeutic concentration:|
|18 years and up:||Lidocaine 2.0-5.0 mcg/mL|
|MEGX 0.5-2.0 mcg/mL|
|18 years and up:||Lidocaine >8 mcg/mL|
|MEGX >8 mcg/mL|
Interpretation Type: Interpretive Guidelines
Critical Calls: yes
Result of "BELOW DETECTION" indicates that the result is below method detection limit of 0.1 mcg/mL. The half-life is approximately 1-2 hours. Lidocaine is metabolized to monoethylglycine-xylidine (MEGX).
This test was developed and its performance characteristics determined by the UWHC Clinical Laboratories. This test meets the standards for clinical testing. This test should not be regarded as investigational or for research use. The US Food and Drug Administration (FDA) has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.