Feb 5, 2018




Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Toxicology


Lithium (LI) Toxicology Lab Test

Name: Lithium

Test Name: Lithium

Health Link Test Code: LI

LIS Test Code: LI

CPT Code(s): 80178

Methodology: Colorimetric

Clinical Information:

Manic depressive affective disorder.

Days Performed: Daily, 24 hours.

In-Lab Turnaround Time: 4 hours.

Stat In-Lab Turnaround Time: 1 hour.

Specimen: Blood

Collection Container: Red cap with yellow ring (SST)

Also Acceptable: Red top

Collection Instructions:

Collect specimen for trough level prior to morning dose. This level should be collected 12 hours after the evening dose.

Collection Volume: 2 mL

Pediatric Collection Volume: 0.5 mL

Stability Ambient:

24 hours

Stability Refridgerated:

7 days

Stability Frozen:

6 months

Sample Analyzed: Serum

Testing Volume: 1 mL

Pediatric Testing Volume: 0.2 mL

Specimen Processing:

Centrifuge. If a complete barrier has not formed, transfer cell-free serum to plastic vial. Refrigerate.

Specimen Transport:

Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.

Unacceptable Criteria:

Green top tubes (with black, white or yellow-ring) are not acceptable.



0.6-1.20 mmol/L

Interpretation Type: Reference Interval

Critical Calls: yes

Additional Information:

Result of BELOW indicates that the result is below the method detection limit of 0.20 mmol/L. Serum lithium concentrations peak 2-4 hours after dose. Half-life is 24 hours in adults, 18 hours in adolescents, and greater than 36 hours in the elderly.