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Jan 30, 2018

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Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Toxicology

Cocaine, Urine Screen

Cocaine, Urine Screen (HCCOCMET) Toxicology Lab Test

Name: Cocaine, Urine Screen

Test Name: Cocaine, Urine Screen

Health Link Test Code: HCCOCMET

LIS Test Code: COCMET

CPT Code(s): 80307

Included In: Drug Screen, Urine (Stat)

Methodology: Enzyme Immunoassay

Clinical Information:

Qualitative test for benzoylecgonine.

Days Performed: Daily, 24 hours.

Stat In-Lab Turnaround Time: 1 hour.

Specimen: Random urine

Collection Container: Sterile screw cap container

Collection Instructions:

If confirmation is requested on a specimen with a "screen positive" result, 10 mL of urine is needed for the confirmatory analysis.

Collection Volume: 25 mL

Pediatric Collection Volume: 10 mL

Stability Refridgerated:

5 days

Stability Frozen:

>5 days

Sample Analyzed: Urine aliquot

Testing Volume: 2 mL

Pediatric Testing Volume: 0.5 mL

Specimen Processing:

Refrigerate specimen.

Specimen Transport:

Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.

Interpretation:

This is a qualitative screening test. Results will be reported as "not detected" or "screen positive".

Test Limitations:

This is a screening test. Results are to be used for medical purposes only.

Additional Information:

A cut-off value of 300 ng/mL is used to determine whether cocaine and its metabolites are "screen positive". If screening test is reported as "screen positive", confirmation and identification can be made (at additional charge) by a reference lab. Please submit an add-on order within 7 days of collection if confirmatory testing is needed.

 

Cocaine is rapidly metabolized in the human body to benzoylecgonine, which this method will detect. The half-life of benzoylecgonine is relatively long, on the order of 6 hours, and the metabolite may appear in the urine for days. Thus, the presence of benzoylecgonine is solid proof of past use, but the timing of the past use cannot be inferred from the urinalysis alone. (Karch, SB., Karch's Pathology of Drug Abuse, Third Edition, 2002; pg.65)