Name: Legionella Urinary Ag
Test Name: Legionella Urinary Ag
Health Link Test Code: GM4910
LIS Test Code: LUAG
CPT Code(s): 87449
Methodology: Immunochromatographic Assay
Detects the presence of Legionella pneumophila serogroup 1 antigen in urine.
Days Performed: Mon-Fri.
In-Lab Turnaround Time: 1 - 3 days.
Stat In-Lab Turnaround Time: Not available stat.
Collection Container: Sterile screw cap container
Collection Volume: 1 mL
Pediatric Collection Volume: 1 mL
Freeze if sample will not be assayed within 14 days.
Sample Analyzed: Urine aliquot
Urine may be transported at room temperature for up to 24 hours following collection. Specimen may also be refrigerated up to 14 days or frozen for longer periods. Boric acid may be used as a preservative. Transport specimen to the laboratory.
LIMIT: One specimen every 7 days. Specimens that are inappropriately transported are not acceptable.
Interpretation Type: Expected Results
Test will not detect infections caused by other Legionella pneumophila serogroups or other Legionella species.
This test in not validated for diuretic urines nor outpatient population.
Antigen excretion may begin as early as 3 days after onset of symptoms and persist for up to one year.
A negative result indicates a presumptive negative for Legionella pneumophila serogroup 1 antigen in urine, suggesting no recent or current infection.
Infection due to Legionella cannot be ruled out since other serogroups and species may cause disease, the antigen may not be present in urine in early infection, or the level of antigen present in the urine may be below the detection limit of the test.
Culture is recommended to detect causative agents other than Legionella pneumophila serogroup 1 and to recover L. pneumophila serogroup 1 when antigen is not detected in the urine.
A positive result suggests current or past infection and is not definitive for infection without other supporting evidence.