Name: Hepatitis B Core Ab, IgM
Test Name: Hepatitis B Core Ab, IgM
Health Link Test Code: XHBCM
LIS Test Code: CORM
CPT Code(s): 86705
Methodology: Chemiluminescent Immunoassay
Days Performed: Daily, 24 hours.
In-Lab Turnaround Time: 4 hours.
Stat In-Lab Turnaround Time: Not available stat.
Collection Container: Red cap with yellow ring (SST)
Also Acceptable: Red top
Collection Volume: 3 mL
Pediatric Collection Volume: 1.5 mL
Sample Analyzed: Serum
Testing Volume: 1 mL
Pediatric Testing Volume: 0.5 mL
Centrifuge. If complete barrier is not formed, transfer cell-free serum to plastic vial. Refrigerate.
Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.
Reference Interval: Nonreactive
Nonreactive: The presence of antibody to hepatitis B core without IgM indicates past infection with hepatitis B. Anti-hepatitis B core antibody persists for life.
Borderline: Repeat testing if clinically warranted.
Reactive: The presence of IgM antibody to hepatitis B core represents acute infection or acute resolving infection. Anti-HBc IgM generally persists for up to 6 months if the disease resolves. In patients who have chronic HBV infection, IgM anti-HBc can persist at low levels during viral replication. Persons with exacerbations of chronic infection can test positive for IgM anti-HBc.
Interpretation of Hepatitis B Test Result
Results may be affected if patient has developed heterophillic antibodies due to exposure to animal based protein products.
The assay performance characteristics have not been established for cadaver specimens, heat inactivated specimens and body fluids other than serum.
This method is approved for diagnostic testing only. It is not approved for screening tissue donors that fall under FDA's HCT/P requirements.