Name: CMV Ab, IgG
Test Name: CMV Ab, IgG
Health Link Test Code: XCMVG
LIS Test Code: CMVIGG
CPT Code(s): 86644
Methodology: Enzyme Immunoassay
Screening test to detect prior exposure to CMV.
Days Performed: Daily.
In-Lab Turnaround Time: 1 day.
Stat In-Lab Turnaround Time: Not available stat.
Collection Container: Red cap with yellow ring (SST)
Also Acceptable: Red top
Collection Volume: 2 mL
Pediatric Collection Volume: 0.3 mL
-25 ± 6°C acceptable with only one freeze/thaw cycle.
Sample Analyzed: Serum
Testing Volume: 1 mL
Pediatric Testing Volume: 0.15 mL
Centrifuge. If a complete barrier has not formed, transfer cell-free serum to plastic vial. Refrigerate.
Transport specimen to UWHC Hospital Laboratory. Transport with coolant pack if coming from clinic location.
|Negative:||CMV IgG antibody was not detected.|
|Equivocal:||Repeat testing within a week recommended, if clinically indicated.|
|Positive:||May indicate past or present CMV infection.|
Interpretation Type: Interpretive Guidelines
This method is approved for diagnostic testing only. It is not approved for screening tissue donors that fall under FDA's HCT/P requirements.
The presence of IgG antibodies in a single specimen is not sufficient to distinguish between active or past infection.
Patients suspected of having primary or active infection could be tested for the presence of IgM antibodies to CMV or CMV DNA by PCR.
Individuals with acute CMV infection may not exhibit any detectable IgG antibodies at the early stage of infection.