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May 18, 2015

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100

UWHC,UWMF,

Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Infectious Disease

CMV Ab, IgG

CMV Ab, IgG (XCMVG) Infectious Disease Lab Test

Name: CMV Ab, IgG

Test Name: CMV Ab, IgG

Health Link Test Code: XCMVG

LIS Test Code: CMVIGG

CPT Code(s): 86644

Methodology: Enzyme Immunoassay

Clinical Information:

Screening test to detect prior exposure to CMV.

Days Performed: Daily.

In-Lab Turnaround Time: 1 day.

Stat In-Lab Turnaround Time: Not available stat.

Specimen: Blood

Collection Container: Red cap with yellow ring (SST)

Also Acceptable: Red top

Collection Volume: 2 mL

Pediatric Collection Volume: 0.3 mL

Stability Ambient:

8 hours

Stability Refridgerated:

5 days

Stability Frozen:

-25 ± 6°C acceptable with only one freeze/thaw cycle.

Sample Analyzed: Serum

Testing Volume: 1 mL

Pediatric Testing Volume: 0.15 mL

Specimen Processing:

Centrifuge. If a complete barrier has not formed, transfer cell-free serum to plastic vial. Refrigerate.

Specimen Transport:

Transport specimen to UWHC Hospital Laboratory. Transport with coolant pack if coming from clinic location.

Interpretation:

 

Negative:  CMV IgG antibody was not detected.
Equivocal: Repeat testing within a week recommended, if clinically indicated.
Positive: May indicate past or present CMV infection.

 

Interpretation Type: Interpretive Guidelines

Test Limitations:

This method is approved for diagnostic testing only.  It is not approved for screening tissue donors that fall under FDA's HCT/P requirements.

Additional Information:

The presence of IgG antibodies in a single specimen is not sufficient to distinguish between active or past infection.

 

Patients suspected of having primary or active infection could be tested for the presence of IgM antibodies to CMV or CMV DNA by PCR.

 

Individuals with acute CMV infection may not exhibit any detectable IgG antibodies at the early stage of infection.