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Jun 30, 2017

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Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Immunology

Varicella-Zoster Ab, IgG

Varicella-Zoster Ab, IgG (VZIGG) Immunology Lab Test

Name: Varicella-Zoster Ab, IgG

Test Name: Varicella-Zoster Ab, IgG

Health Link Test Code: VZIGG

LIS Test Code: VZVIGG

CPT Code(s): 86787

Methodology: ELISA

Clinical Information:

The intent of the test system together with other clinical information is to aid in the determination of immune status, and/or aid in the diagnosis of VZV (Varicella-Zoster Virus).

Days Performed: Three times per week.

In-Lab Turnaround Time: 1 - 4 days.

Specimen: Blood

Collection Container: Red cap with yellow ring (SST)

Also Acceptable: Red top

Collection Volume: 1 mL

Pediatric Collection Volume: 1 mL

Stability Ambient:

8 hours

Stability Refridgerated:

14 days

Stability Frozen:

3 months at 20°C or greater

Sample Analyzed: Serum

Testing Volume: 0.5 mL

Pediatric Testing Volume: 0.3 mL

Specimen Processing:

Centrifuge. Transfer cell-free serum to plastic vial. Refrigerate.

Specimen Transport:

Transport specimen to Laboratory. Transport with coolant pack if coming from clinic locations.

Unacceptable Criteria:

Grossly hemolyzed/lipemic, heat-treated serum, microbially contaminated and serum containing heavily-visible particulate.

Interpretation:

Negative: No detectable IgG antibodies to VZV.  Patient is presumed to be non-immune and is susceptible to a primary infection.
Equivocal: Immune status cannot be determined.  If clinically warranted, a second sample should be taken at least fourteen days after the first.
Positive: Reactive for IgG antibodies to VZV, indicating a current or past varicella-zoster infection.  A positive IgG antibody level in the absence of current clinical symptoms indicates immunity to VZV.

 

All equivocal test results will be repeated within two working days.

Additional Information:

If a numerical value and interpretation of the assay is needed please refer to the Occupational MMR/VZV Antibody Assessment Panel at an approved reference laboratory.