Name: Cardiolipin Ab, IgM
Test Name: Cardiolipin Ab, IgM
Health Link Test Code: HCCARIGM
LIS Test Code: CARIGM
CPT Code(s): 86147
Included In: Cardiolipin Ab, IgG/IgM
Methodology: Enzyme Immunoassay
Cardiolipin Ab testing is performed for evaluation of hypercoagulable state that may be associated with venous or arterial thromboemboli. Diseases associated with cardiolipin antibodies include SLE, drug-induced lupus, other connective tissue diseases and primary anti-phospholipid antibody syndrome.
Days Performed: Mon-Fri, dayshift - day varies.
In-Lab Turnaround Time: 1 week.
Stat In-Lab Turnaround Time: Not available stat.
Collection Container: Red top
Also Acceptable: Red cap with yellow ring (SST)
Collection Volume: 3 mL
Pediatric Collection Volume: 1 mL
No limit at -20° C. Note: Avoid repeat freeze and thaw.
Sample Analyzed: Serum
Testing Volume: 1 mL
Pediatric Testing Volume: 0.3 mL
Centrifuge. Transfer cell-free serum to plastic vial. Refrigerate.
Transport serum sample to UWHC Hospital Laboratory. Transport with coolant pack if coming from clinic location.
Grossly hemolyzed, lipemic and turbid specimens are not acceptable.
0 days and up:
|IgM:||Negative (0-13 MPL)|
Cardiolipin Ab, IgM Interpretive Guidelines:
Cardiolipin Ab, IgM results are obtained with the INOVA QUANTA Lite ACA IgM (HRP) ELISA kits.
Interpretation Type: Expected Results
Rheumatoid factor, usually an IgM autoantibody, can interfere with the determination of the IgM aCL. Cardiolipin Ab, IgG and IgM values obtained with different manufacturers' assay methods may not be used interchangeably. The magnitude of the reported IgG or IgM levels cannot be correlated to an endpoint titer.