Name: HLA B Locus
Test Name: HLA B Locus
Health Link Test Code: HCBLOCS (if Pre-Tx) , HCBLOCB (if Post-Tx)
LIS Test Code: LRBLOCS (if Pre-Tx), LRBLOCB (if Post-Tx)
CPT Code(s): 81373
Methodology: Reverse SSO detected by Luminex xMAP (Multi-Analyte Profiling)
HLA-B locus low-to-mid level resolution typing typically used to match donor and recipients for organ transplantation and HLA-matched platelet transfusion. Also may be used to identify the presence of HLA class I alleles associated with some diseases (e.g. B27 for ankylosing spondylitis) For pharmacogenomic relationships (e.g. HLA-B*5701 for Abacavir refer to HLA B for Abacavir Sensitivity [HCHLABAS]. For B*1502 or Carbamazepine sensitivity refer to HLA B for Carbatrol Sensitivity [HCHLABCS]).
Commonly ordered with HLA-A and HLA-C locus for class I HLA typing. HLA-B27 single antigen testing (for association with Ankylosing Spondylitis) is available separately. Refer to entry HLA-B27 [XHLA].
Days Performed: Mon-Fri.
In-Lab Turnaround Time: 1 week.
Stat In-Lab Turnaround Time: Not available stat.
No transfusions (RBC, WBC, Platelets) within 24 hours prior to collection.
Collection Container: Lavender top
Also Acceptable: Yellow top(with ACD-A/B anticoagulant)
Collection Volume: 4 mL
Pediatric Collection Volume: 2 mL
Sample Analyzed: Whole Blood
Testing Volume: 4 mL
Pediatric Testing Volume: 2 mL
Do not centrifuge.
Transport whole blood specimen at room temperature or refrigerated to UWHC Hospital Laboratory.
A written interpretive report will be provided.
This test was developed and its performance characteristics determined by this laboratory. It has not been cleared or approved by the US Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This test is used for clinical purposes. It should not be regarded as investigational or for research. This laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA-88) as qualified to perform high complexity clinical laboratory testing.