Name: Alpha 2 Antiplasmin
Test Name: Alpha 2 Antiplasmin
Health Link Test Code: HCA2AP
LIS Test Code: A2AP
CPT Code(s): 85410
Methodology: Activity (Chromogenic)
Test is used for the chromogenic determination of plasmin inhibitor (alpha 2-antiplasmin) activity in human plasma. Alpha 2-antiplasmin is the major fast-acting inhibitor of the fibrinolytic enzyme plasmin and an important regulator of the fibrinolytic system.
Days Performed: Mon-Fri, dayshift - day varies. Specimens are accepted at any time. Testing required during off hours must be approved by a Coagulation physician. Call 263-5005 before collection.
In-Lab Turnaround Time: 4 - 10 days.
Stat In-Lab Turnaround Time: 1 day.
Collection Container: Light blue top (3.2% NaCitrate)
Do NOT draw through a line containing heparin. The venipuncture MUST be atraumatic to avoid hemolysis and contamination with tissue factors and platelets. Tube must be allowed to fill completely.
Collection Volume: Full 3.5 mL tube
Pediatric Collection Volume: Pediatric tube filled to fill mark
4 hours on a spun tube
2 weeks at -20°C; 6 month at -70°C
Sample Analyzed: Plasma
Testing Volume: 1 mL
Pediatric Testing Volume: 0.5 mL
Centrifuge specimen to yield platelet poor plasma (platelet count should be less than 10 K/µL). Separate plasma and transfer to plastic tube or vial. Freeze plasma within 4 hours of collection at -20°C or below.
Transport whole blood specimen at room temperature to UWHC Hospital Laboratory within 4 hours of collection. See Specimen Processing for instructions if transport criteria are not met. Transport frozen plasma aliquot on dry ice to UWHC Hospital Laboratory.
Hemolyzed specimens, clotted specimens, partially filled tubes and whole blood specimens greater than 4 hours old when received by the laboratory are not acceptable.
|6 months and up:||85-150% NPP|
Alpha 2 Antiplasmin in normal, full-term newborn infants may have borderline low or mildly decreased levels (>50%) which reach adult levels within 5 to 7 days postnatal. Healthy, premature infants (30-36 weeks gestation) may have mildly decreased levels which reach adult levels around 90 days postnatal.
Interpretation Type: Reference Interval