Apr 2, 2015




Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Coagulation

D-Dimer, Quantitative

D-Dimer, Quantitative (GM1332) Coagulation Lab Test

Name: D-Dimer, Quantitative

Test Name: D-Dimer, Quantitative

Health Link Test Code: GM1332


CPT Code(s): 85379

Methodology: Immunoturbidimetry

Days Performed: Daily, 24 hours.

In-Lab Turnaround Time: 4 hours.

Stat In-Lab Turnaround Time: 1 hour.

Specimen: Blood

Collection Container: Light blue top (3.2% NaCitrate)

Collection Instructions:

The venipuncture MUST be atraumatic to avoid hemolysis and contamination with tissue factors and platelets. Tube MUST be allowed to fill up to the "fill" line indicated on the tube.


If unable to collect 1.8 ml tube (pediatrics only) please call UWHC Coagulation Lab at (608) 263-9617 or UWHC Special Coagulation Lab at (608) 263-5005 for alternate tube and instructions.

Collection Volume: 3.5 mL

Pediatric Collection Volume: 1.8 mL

Stability Ambient:

8 hours

Stability Refridgerated:

Not acceptable

Stability Frozen:

1 month

Sample Analyzed: Plasma

Testing Volume: 1 mL

Pediatric Testing Volume: 0.15 mL

Specimen Processing:

If transport time exceeds 4 hours, centrifuge and transfer cell-free plasma to a plastic vial. Freeze plasma.

Specimen Transport:

Transport whole blood specimen to UWHC Hospital Laboratory within 4 hours of collection. Otherwise, transport frozen plasma aliquot on dry ice.

Unacceptable Criteria:

Hemolyzed specimens, clotted specimens, partially filled tubes and whole blood specimens greater than 4 hours old when received by the laboratory are not acceptable.


0.00-0.49 mcg/mL FEU


A D-dimer level < 0.5 mcg/mL FEU is inconsistent with venous thromboembolic disease. In a patient with a low or intermediate pretest probablility, venous thromboembolic disease can be ruled out if the D-dimer level is < 0.5 mcg/mL FEU. Elevated D-dimer levels are nonspecific and may be seen in recent surgery, acute infection, malignancy and renal disease. (Wells et al, NEJM 349:1227-30; Ginsberg et al, Ann Int Med 129:1006-11)

Interpretation Type: Reference Interval

Additional Information:

This method is a quantitative method which replaces Fibrin Degradation Products.