Test Name: Sirolimus
Health Link Test Code: HCSIRO
LIS Test Code: SIRO
CPT Code(s): 80195
Days Performed: Daily.
In-Lab Turnaround Time: 1 day.
Sirolimus level should be determined on trough specimen collected just prior to administration of the next dose.
Collection Container: Lavender top
Collect specimen just before taking next dose.
Collection Volume: 4 mL
Pediatric Collection Volume: 0.5 mL
Sample Analyzed: Whole Blood
Do NOT centrifuge or separate plasma. SEND WHOLE BLOOD.
Transport specimen at ambient temperature to laboratory.
A definitive therapeutic concentration for Sirolimus has not been established. A concentration of 5-15 ng/mL is generally considered to be therapeutic for individuals 18 years old and older. Test is performed by immunassay on an Abbott Architect.
Interpretation Type: Interpretive Guidelines
Critical Calls: yes
The reportable range for sirolimus is 2 - 60 ng/mL. Results of less than 2 ng/ mL will be reported as less than 2 ng/mL.