Jun 27, 2016




Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Chemistry


Sirolimus (HCSIRO) Chemistry Lab Test

Name: Sirolimus

Test Name: Sirolimus

Health Link Test Code: HCSIRO

LIS Test Code: SIRO

CPT Code(s): 80195

Methodology: Immunoassay

Clinical Information:


Days Performed: Daily.

In-Lab Turnaround Time: 1 day.

Patient Preparation:

Sirolimus level should be determined on trough specimen collected just prior to administration of the next dose.

Specimen: Blood

Collection Container: Lavender top

Collection Instructions:

Collect specimen just before taking next dose.

Collection Volume: 4 mL

Pediatric Collection Volume: 0.5 mL

Stability Ambient:

7 days

Stability Refridgerated:

7 days

Sample Analyzed: Whole Blood

Specimen Processing:

Do NOT centrifuge or separate plasma. SEND WHOLE BLOOD. 

Specimen Transport:

Transport specimen at ambient temperature to laboratory.


A definitive therapeutic concentration for Sirolimus has not been established. A concentration of 5-15 ng/mL is generally considered to be therapeutic for individuals 18 years old and older. Test is performed by immunassay on an Abbott Architect.

Interpretation Type: Interpretive Guidelines

Critical Calls: yes

Additional Information:

The reportable range for sirolimus is 2 - 60 ng/mL. Results of less than 2 ng/ mL will be reported as less than 2 ng/mL.