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Jun 27, 2016

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Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Chemistry

Tacrolimus

Tacrolimus (HCTAC) Chemistry Lab Test

Name: Tacrolimus

Test Name: Tacrolimus

Health Link Test Code: HCTAC

LIS Test Code: TAC

CPT Code(s): 80197

Methodology: Immunoassay

Clinical Information:

Immunosuppressive

Days Performed: Daily.

In-Lab Turnaround Time: 1 day.

Patient Preparation:

Tacrolimus level should be determined on trough specimen collected just prior to administration of the next dose.

Specimen: Blood

Collection Container: Lavender top

Collection Instructions:

Collect specimen just before taking next dose.

Collection Volume: 4 mL

Pediatric Collection Volume: 0.5 mL

Stability Ambient:

7 days

Stability Refridgerated:

7 days

Sample Analyzed: Whole Blood

Specimen Processing:

Do NOT centrifuge or separate plasma. SEND WHOLE BLOOD.

Specimen Transport:

Transport specimen at ambient temperature to laboratory.

Interpretation:

Definitive therapeutic concentration for Tacrolimus has not been established. A concentration of 5-15 ng/mL is generally considered to be therapeutic for individuals 18 years old and older. Test is performed by immunoassay on an Abbott Architect.

Interpretation Type: Interpretive Guidelines

Critical Calls: yes

Additional Information:

The reportable range for tacrolimus is 2-60 ng/mL.  Results of less than 2 ng/mL will be reported as less than 2 ng/mL.