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Oct 18, 2016

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Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Chemistry

Cyclosporine

Cyclosporine (XCYCA) Chemistry Lab Test

Name: Cyclosporine

Test Name: Cyclosporine

Health Link Test Code: XCYCA

LIS Test Code: CSTD

CPT Code(s): 80158

Methodology: Immunoassay

Clinical Information:

Immunosuppressive

Days Performed: Daily.

In-Lab Turnaround Time: 1 day.

Patient Preparation:

Cyclosporine level should be determined on trough specimen collected just prior to administration of the next dose.

Specimen: Blood

Collection Container: Lavender top

Collection Instructions:

Collect specimen just before taking next dose.

Collection Volume: 4 mL

Pediatric Collection Volume: 0.5 mL

Stability Ambient:

7 days

Stability Refridgerated:

7 days

Sample Analyzed: Whole Blood

Specimen Processing:

Do NOT centrifuge or separate plasma. SEND WHOLE BLOOD.

Specimen Transport:

Transport specimen at ambient temperature to laboratory.

Interpretation:

A definitive therapeutic concentration for Cyclosporine has not been established.  A concentration of 50-300 ng/mL is generally considered to be therapeutic for individuals 18 years old and older. Test is performed by immunoassay on an Siemens ExL.

Interpretation Type: Interpretive Guidelines

Critical Calls: yes

Additional Information:

The reportable range for cyclosporine is 25-2000 ng/mL. Samples less than 25 ng/mL will be reported as < 25 ng/mL.