Jan 8, 2018




Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Chemistry


Alpha-1-Antitrypsin (XA1A) Chemistry Lab Test

Name: Alpha-1-Antitrypsin

Test Name: Alpha-1-Antitrypsin

Health Link Test Code: XA1A

LIS Test Code: AAT

CPT Code(s): 82103

Methodology: Turbidometric

Clinical Information:

Alpha-1-antitrypsin test aids in the diagnosis of alpha-1-antitrypsin deficiency associated with familial pulmonary emphysema and liver disease. Decreased serum alpha-1-antitrypsin may also be seen in prematurity, severe liver disease, malnutrition, renal protein loss and gastrointestinal protein loss. Serum alpha-1-antitrypsin may be increased in infection, neoplasia, pregnancy and use of birth control pills.

Days Performed: Daily, 24 hours.

In-Lab Turnaround Time: 4 hours.

Stat In-Lab Turnaround Time: 1 hour.

Specimen: Blood

Collection Container: Green cap with yellow ring (PST)

Also Acceptable: Green top, Red cap with yellow ring (SST), Red top

Collection Volume: 1 mL

Pediatric Collection Volume: 0.4 mL

Stability Ambient:

3 months

Stability Refridgerated:

5 months

Stability Frozen:

3 months

Sample Analyzed: Plasma or serum

Testing Volume: 0.5 mL

Pediatric Testing Volume: 0.2 mL

Specimen Processing:

Centrifuge within 2 hours of draw. If a complete barrier has not formed, transfer cell-free plasma/serum to clear plastic vial. Refrigerate.

Specimen Transport:

Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.


0 days and up: 90-200 mg/dL

Interpretation Type: Reference Interval