Feb 5, 2018




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Complement C4

Complement C4 (XC4) Chemistry Lab Test

Name: Complement C4

Test Name: Complement C4

Health Link Test Code: XC4

LIS Test Code: C4

CPT Code(s): 86160

Methodology: Immunoturbidimetry

Clinical Information:

Complement levels are requested in the following clinical situations: workup for immunodeficiency, assessment of SLE, assessment of disease activity in SLE, assessment of vasculitis (including glomerulonephritis) and assessment of disease activity in vasculitis.

Days Performed: Daily, 24 hours.

In-Lab Turnaround Time: 4 hours.

Stat In-Lab Turnaround Time: 1 hour.

Specimen: Blood

Collection Container: Red cap with yellow ring (SST)

Also Acceptable: Green cap with yellow ring (PST), Green top, Red top

Collection Volume: 4 mL

Pediatric Collection Volume: 0.4 mL

Stability Refridgerated:

2 days

Sample Analyzed: Serum or plasma

Testing Volume: 0.5 mL

Pediatric Testing Volume: 0.2 mL

Specimen Processing:

Centrifuge. If a complete barrier has not formed, transfer cell-free serum/plasma to plastic vial. Refrigerate.

Specimen Transport:

Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.

Unacceptable Criteria:

Grossly hemolyzed, lipemic and turbid specimens are not acceptable.


Age Male (mg/dL) Female (mg/dL)
1-14 years 14-44 13-46
15 years and up 15-53 15-57


Interpretation Type: Reference Interval