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Jan 8, 2018

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C Reactive Protein, High Sensitivity

C Reactive Protein, High Sensitivity (HSCRP) Chemistry Lab Test

Name: C Reactive Protein, High Sensitivity

Test Name: C Reactive Protein, High Sensitivity

Health Link Test Code: HSCRP

LIS Test Code: HSCRP

CPT Code(s): 86141

Methodology: Turbidometric

Days Performed: Daily, 24 hours.

In-Lab Turnaround Time: 4 hours.

Stat In-Lab Turnaround Time: 1 hour.

Specimen: Blood

Collection Container: Green cap with yellow ring (PST)

Also Acceptable: Green top, Red cap with yellow ring (SST), Red top

Collection Volume: 4 mL

Pediatric Collection Volume: 0.5 mL

Stability Ambient:

15 days

Stability Refridgerated:

2 months

Stability Frozen:

3 years

Sample Analyzed: Plasma or serum

Testing Volume: 0.5 mL

Pediatric Testing Volume: 0.2 mL

Specimen Processing:

Centrifuge. If a complete barrier has not formed, transfer cell-free plasma/serum to clear plastic vial. Refrigerate.

Specimen Transport:

Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.

Interpretation:

When assessing risk of coronary heart disease, hs-CRP values should be used in conjunction with lipid values and other risk factors. Values in the 2nd and 3rd tertiles should be repeated and the average of the two values should be used for risk assessment. CRP is an acute phase reactant, so this test should not be obtained within 4 weeks of a systemic illness or myocardial infarction. Values greater than 5.0 mg/L may represent systemic inflammation.

Risk assessment: AHA/CDC Statement (Circulation 2003;107:499-511)

Tertile 1  < 1.0 mg/L   (low risk)  
Tertile 2  1.0-3.0 mg/L  (average risk)  
Tertile 3  > 3.0 mg/L  (high risk)