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Aug 9, 2015

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Uric Acid for Patients on Rasburicase

Uric Acid for Patients on Rasburicase (HCRASURC) Chemistry Lab Test

Name: Uric Acid for Patients on Rasburicase

Test Name: Uric Acid for Patients on Rasburicase

Health Link Test Code: HCRASURC

LIS Test Code: RASURC

CPT Code(s): 84550

Methodology: Uricase

Days Performed: Daily, 24 hours.

In-Lab Turnaround Time: 2 hours.

Stat In-Lab Turnaround Time: 1 hour.

Specimen: Blood

Collection Container: Green cap with yellow ring (PST)

Also Acceptable: Green top

Collection Instructions:

Sample must be drawn in a pre-chilled tube. Place sample on ice or coolant pack immediatley after drawing.

Collection Volume: 1 mL

Pediatric Collection Volume: 0.4 mL

Stability Refridgerated:

4 hours

Sample Analyzed: Plasma

Testing Volume: 0.5 mL

Pediatric Testing Volume: 0.2 mL

Specimen Processing:

Centrifuge immediately. Transfer cell free plasma to plastic vial. Refrigerate.

Specimen Transport:

Transport specimen with coolant pack to UWHC Hospital Laboratory immediately. Transport with coolant pack if coming from clinic location. Specimen must be received by laboratory within 4 hours of collection.

Unacceptable Criteria:

Samples greater than 4 hours old when received by the UWHC Hospital Laboratory are not acceptable.

Interpretation:

 Male:    Female:  
 Age  mg/dL  Age  mg/dL
 0-4 years  2.0-5.5  0-4 years  2.0-5.5
 5-11 years  3.0-6.0  5-10 years  2.8-6.0
 12-14 years  3.2-7.5  11-17 years  2.8-6.6
 15 years and up  3.5-8.0  18 years and up  2.6-6.0

                    

Interpretation Type: Reference Interval

Test Limitations:

Must be analyzed within 4 hours of collection. Rasburicase (Elitek) will cause enzymatic degradation of uric acid within blood allowed to sit at room temperature, resulting in low uric acid levels. Sample must then be redrawn.

Additional Information:

As per discussion with the UWHC Pharmacy and the manufacturer of rasburicase, this special collection procedure can be discontinued 4 days after the last dose of rasburicase.