Jan 30, 2018




Clinical Hub,Tools & Resources,UWHC Lab Test Directory,Chemistry

CA 125

CA 125 (XCA125) Chemistry Lab Test

Name: CA 125

Test Name: CA 125

Health Link Test Code: XCA125

LIS Test Code: CA125

CPT Code(s): 86304

Methodology: Chemiluminescent Immunoassay

Days Performed: Daily, 24 hours.

In-Lab Turnaround Time: 4 hours.

Stat In-Lab Turnaround Time: 1 hour.

Specimen: Blood

Collection Container: Green cap with yellow ring (PST)

Also Acceptable: Green top, Red cap with yellow ring (SST), Red top

Collection Volume: 1 mL

Pediatric Collection Volume: 0.5 mL

Stability Ambient:

24 hours

Stability Refridgerated:

7 days removed from cells, clot, or gel

24 hours on gel

Stability Frozen:

>7 days

Sample Analyzed: Serum or plasma

Testing Volume: 0.5 mL

Pediatric Testing Volume: 0.15 mL

Specimen Processing:

Centrifuge. If a complete barrier has not formed, transfer cell-free serum to plastic vial. Refrigerate.

Specimen Transport:

Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.


0 days and up: 0-35 Units/mL

Interpretation Type: Reference Interval

Test Limitations:

This method is intended to be used as an aid in the management of ovarian cancer patients with metastatic disease by monitoring the progression of regression of disease in response to treatment.  The Abbott ARCHITECT CA125 II assay is not intended for screening or diagnosis of ovarian cancer.

Results may be affected if patient has developed heterophillic antibodies due to exposure to animal based protein products.

A high dose hook effect is not seen up to 180,000 U/mL.

Additional Information:

The Abbot ARCHITECT CA125 II method is used.  Results obtained with different assay methods or kits cannot be used interchangeably.