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Dec 18, 2017

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Beta-hydroxybutyrate

Beta-hydroxybutyrate (XBOH) Chemistry Lab Test

Name: Beta-hydroxybutyrate

Test Name: Beta-hydroxybutyrate

Health Link Test Code: XBOH

LIS Test Code: BOH

CPT Code(s): 82010

Methodology: Enzymatic

Days Performed: Daily, 24 hours.

In-Lab Turnaround Time: 4 hours.

Stat In-Lab Turnaround Time: 1 hour.

Specimen: Blood

Collection Container: Green cap with yellow ring (PST)

Also Acceptable: Green top, Red cap with yellow ring (SST), Red top

Collection Volume: 1 mL

Pediatric Collection Volume: 0.4 mL

Stability Ambient:

24 hours

Stability Refridgerated:

4 days

Stability Frozen:

1 year

Sample Analyzed: Plasma or serum

Testing Volume: 0.5 mL

Pediatric Testing Volume: 0.2 mL

Specimen Processing:

Centrifuge. Redraw specimen if hemolysis is present. If a complete barrier has not formed, transfer cell-free serum to plastic vial. Refrigerate.

Specimen Transport:

Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.

Unacceptable Criteria:

Hemolyzed specimens are not acceptable.

Interpretation:

0 days and up: 0.02-0.27 mmol/L

Interpretation Type: Reference Interval

Additional Information:

BOH is one of three ketone bodies (BOH, acetone, and acetoacetate) that are commonly found in blood and urine. Increased blood concentrations of BOH, acetone and acetoacetate are observed in conditions associated with decreased availability of carbohydrates (e.g. starvation, anorexia nervosa, prolonged vomiting, and chronic alcohol consumption) or decreased use of carbohydrates (e.g. untreated diabetes mellitus). Decreased carbohydrate metabolism forces the body to acquire its energy production from fat, with the products of fat metabolism appearing in the blood and urine (ketoacidosis). BOH is the ketone body of choice when diagnosing or monitoring these conditions, because its blood levels rise quickly during early phases of these illnesses and respond as expected when successful treatment is initiated.

This test was performed using a modification of an FDA approved method. The performance characteristics of this test were determined by the UWHC Clinical Laboratories and meet the standards for clinical testing.