Test Name: Beta-hydroxybutyrate
Health Link Test Code: XBOH
LIS Test Code: BOH
CPT Code(s): 82010
Days Performed: Daily, 24 hours.
In-Lab Turnaround Time: 4 hours.
Stat In-Lab Turnaround Time: 1 hour.
Collection Container: Green cap with yellow ring (PST)
Also Acceptable: Green top, Red cap with yellow ring (SST), Red top
Collection Volume: 1 mL
Pediatric Collection Volume: 0.4 mL
Sample Analyzed: Plasma or serum
Testing Volume: 0.5 mL
Pediatric Testing Volume: 0.2 mL
Centrifuge. Redraw specimen if hemolysis is present. If a complete barrier has not formed, transfer cell-free serum to plastic vial. Refrigerate.
Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.
Hemolyzed specimens are not acceptable.
0 days and up: 0.02-0.27 mmol/L
Interpretation Type: Reference Interval
BOH is one of three ketone bodies (BOH, acetone, and acetoacetate) that are commonly found in blood and urine. Increased blood concentrations of BOH, acetone and acetoacetate are observed in conditions associated with decreased availability of carbohydrates (e.g. starvation, anorexia nervosa, prolonged vomiting, and chronic alcohol consumption) or decreased use of carbohydrates (e.g. untreated diabetes mellitus). Decreased carbohydrate metabolism forces the body to acquire its energy production from fat, with the products of fat metabolism appearing in the blood and urine (ketoacidosis). BOH is the ketone body of choice when diagnosing or monitoring these conditions, because its blood levels rise quickly during early phases of these illnesses and respond as expected when successful treatment is initiated.
This test was performed using a modification of an FDA approved method. The performance characteristics of this test were determined by the UWHC Clinical Laboratories and meet the standards for clinical testing.