Test Name: Alpha-Fetoprotein
Health Link Test Code: XAFPTM
LIS Test Code: AFP
CPT Code(s): 82105
Methodology: Chemiluminescent Immunoassay
Days Performed: Daily, 24 hours.
In-Lab Turnaround Time: 4 hours.
Stat In-Lab Turnaround Time: Not available stat.
Collection Container: Red cap with yellow ring (SST)
Also Acceptable: Red top
Collection Volume: 1 mL
Pediatric Collection Volume: 0.5 mL
Sample Analyzed: Serum
Testing Volume: 0.5 mL
Pediatric Testing Volume: 0.15 mL
Centrifuge. If a complete barrier has not formed, transfer cell-free serum to plastic vial. Refrigerate.
Transport specimen to the laboratory. Transport with coolant pack if coming from clinic location.
8 months and up: 0.0-8.8 ng/mL
Reference range for newborns is not available but concentrations over 200,000 have been reported in newborns. AFP gradually declines as the infant matures. At 8 months of age, the normal AFP level of infants approaches the adult level.
Pediatric Reference: Serum Alpha Fetoprotein (AFP) Levels in Normal Infants, Pediatr. Res 15:50-52 1981
Interpretation Type: Expected Results
Effective Date of Reference Range: Mon, 10 Aug 2015 00:00:00 CDT
Results may be affected if patient has developed heterophilic antibodies due to exposure to animal based protein products.
A high dose hook effect is not seen up to 10,000,000 ng/mL.