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Alteplase Contraindications

Alteplase Contraindications - Clinical Hub, References, Comprehensive Stroke Program, Thrombolysis

Focus

Updated 10/3/2016

Contraindications in the 3 hour window

Genentech package insert 2015

Demaerschalk, et al. Scientific Rationale for the Inclusion and Exclusion Criteria for Intravenous Alteplase in Acute Ischemic Stroke. Stroke 2015

Additional Contraindications in the 4.5 hour window

Werner Hacke, et. al. for the ECASS Investigators. NEJM 2008