Oral Targretin (Bexarotene)
Targretin is used for treatment of certain
types of skin cancer (cutaneous T-cell
lymphoma or CTCL).
Women who are pregnant, or who may
become pregnant during treatment must not
use this medicine. Severe birth defects can
occur. Two forms of birth control must be
used for 1 month before starting, and 1
month after treatment.
Your doctor will prescribe the amount of
medicine for you.
Headache, rash, nausea, vomiting, dry
skin, diarrhea, or trouble sleeping.
Less common- yellowing eyes and skin,
dark urine, vision changes, unusual
This medicine can make it harder for the
body to fight an infection.
Tell your doctor right away if you
develop any signs of an infection, such
as fever, chills, or a sore throat.
Tell your doctor if you have a history of
heart disease, high cholesterol or triglyceride
levels, pancreatitis, diabetes, kidney, liver,
or thyroid problems. This medicine may
make you more sun sensitive. Wear sun
screen or sunblock, and clothing to protect
Gemfibrozil, claithromycin, erythromycin,
cimetidine, itraconazole, ketoconazole,
nefazodone, phenytoin, phenobarbital,
rifampin, vitamin A. Do not eat grapefruit
or drink grapefruit juice.
If you miss a dose, take it as soon as you
remember. If it is near the time of the next
dose, skip the missed dose and go back to
your usual dosing schedule. Do not take
two doses to catch up.
Dermatology Clinic: (608) 265-0700.
After hours, nights, holidays and weekends
this number will give you the paging
operator. Ask for the Dermatology doctor
on call. Leave your name and phone
number with the area code. The doctor will
call you back.
If you live outside the area, call:
Your health care team may have given you this information as part of your care. If so, please use it and call if you
have any questions. If this information was not given to you as part of your care, please check with your doctor. This
is not medical advice. This is not to be used for diagnosis or treatment of any medical condition. Because each
person’s health needs are different, you should talk with your doctor or others on your health care team when using
this information. If you have an emergency, please call 911. Copyright © 8/2016 University of Wisconsin Hospitals
and Clinics Authority. All rights reserved. Produced by the Department of Nursing HF#6401.