Clinical Hub,Patient Education,Health and Nutrition Facts For You,Transplant

Organ Transplantation: Food Drug Interactions (5640)

Organ Transplantation: Food Drug Interactions (5640) - Clinical Hub, Patient Education, Health and Nutrition Facts For You, Transplant


Organ Transplantation: Food-Drug Interactions

If you are taking drugs such as prednisone,
you may hold (retain) water, gain weight,
and have an increase in your appetite. Long-
term use may also decrease your strength of
your bones and increase your risk of

To prevent “holding” water, decrease your
salt (sodium) intake.

ξ Limit the amount of processed foods
like frozen dinners, packaged
entrees, and canned soups.
ξ Restrict your intake of salted or
smoked meat or fish. Avoid
luncheon meats, bratwurst, and
ξ Try using herbs and spices such as
garlic or onion powder instead of
garlic or onion salt. One good spice
that does not contain salt is Mrs.
Dash Original Blend Spice
ξ Read food labels to pick the products
lowest in salt.
ξ Be careful using foods that are high
in salt like ketchup, pickles, relish
and sauerkraut.

You may be hungrier while taking these
drugs. If you do not want to gain weight,
you may have to control the amount of
calories and fat you eat. Eat only at meal
times and limit your portion sizes. If you are
still hungry, fill up on raw vegetables and
fresh fruits.

To prevent bone weakness and fractures, you
will need to increase your calcium intake.
Milk and milk products are the best sources
of calcium. Antacids like Tums or
Rolaids also contain calcium. Each tablet
contains 200 mg of calcium (1 glass of milk
contains 250-300 mg). Your doctor or
dietitian will suggest that you take extra
calcium with Vitamin D or a multivitamin.

While on corticosteroids, you need to make
sure you eat enough protein. Milk, meats,
eggs, peanut butter and dried beans or peas
are high in protein. If your kidneys are
working well, you should get at least 2-3
protein servings a day. Ask your dietitian
for serving ideas.

In some patients, long-term use of
corticosteroids raises blood sugar levels. A
special diet with or without medicines may
be needed to control blood sugar. Your
doctor will discuss this with you if it
becomes needed.

Cyclosporine (Neoral )
· This medicine can be taken with or
without food.
· Do not eat grapefruit or drink grapefruit
· Do not take extra potassium or use salt
substitutes that contain potassium while
taking this drug.

Tacrolimus (Prograf )
· This medicine may be taken with or
without food as long as consistency is
maintained from day to day.
· Do not eat grapefruit or drink grapefruit
· Do not take extra potassium or use salt
substitutes that contain potassium while
taking this drug.

Sirolimus (Rapamune ) or Everolimus
· Do not eat grapefruit or drink grapefruit
· Either take with food or without food
Mycophenolate (Myfortic ) (Cellcept )

· This medicine can be taken with or
without food. It is suggested that you
take it with food to prevent stomach

Dietary Supplements

· Do not take any herbal, dietary, or over-
the-counter supplements unless you
check with your transplant team first.
These may mix with your drugs in a way
that can make them less effective. This
may harm your transplanted organ.

Your health care team may have given you this information as part of your care. If so, please use it and call if you
have any questions. If this information was not given to you as part of your care, please check with your doctor. This
is not medical advice. This is not to be used for diagnosis or treatment of any medical condition. Because each
person’s health needs are different, you should talk with your doctor or others on your health care team when using
this information. If you have an emergency, please call 911. Copyright © 10/2016. University of Wisconsin Hospitals
and Clinics Authority. All rights reserved. Produced by the Department of Nursing. HF#5640