Clinical Hub,Patient Education,Health and Nutrition Facts For You,Respiratory

Nebulized TOBI (5305)

Nebulized TOBI (5305) - Clinical Hub, Patient Education, Health and Nutrition Facts For You, Respiratory


Nebulized TOBI ≤

TOBI ≤ is an antibiotic solution that is breathed (inhaled) into the lungs. TOBI ≤ is helpful in
fighting lung infections, reducing the number of days in the hospital, and improving lung
function. TOBI ≤ is a clear to light yellow solution. It comes in a sterile, single-dose plastic vial
holding 300mg in 5ml of fluid. TOBI ≤ should be refrigerated and protected from the light. If
you don’t refrigerate it, the color may darken, but it is still safe to use. If the medicine looks
cloudy, has particles floating in it, or has been sitting out for more than 28 days, throw it away.

Each box of TOBI ≤ contains a 28-day supply or 56 vials. These vials are packaged in 14 foil
pouches. Each pouch contains 4 vials, which is enough for 2 days of therapy.

Are there side effects?
Side effects which have sometimes been noted:
ξ Decrease in kidney function
ξ Ringing in the ears or hearing loss
ξ Chest tightness
ξ Muscle weakness
ξ Hoarseness
ξ Wheezing

If any of these side effects occur while breathing in your TOBI ≤, stop the treatment at once and
call your doctor. If you develop any of these side effects at any time you should call your doctor.
If you are pregnant, consult your doctor before using TOBI ≤.

How long do I have to use TOBI ≤?
Before starting the treatment, your doctor will want to know about your cough and obtain
breathing tests (PFTs) to compare the results before and after you have started using TOBI ≤.
This will help your doctor decide if BETHKIS ≤ is helping you. You may be using TOBI ≤ twice
a day for 28 days and then stop the TOBI ≤ for 28 days or as your doctor suggests. Each day you
will do 2 treatments about 12 hours apart; one vial in the morning and one vial in the evening.
Take all of your medicine and airway clearance treatments in the following order. If you have not
been prescribed a certain medicine you can skip that step. Please follow any specific orders you
have been given from your doctor.
1. Bronchodilator (Albuterol)
2. Hypertonic Saline (Hyper-Sal™)
3. DNase (Pulmozyme®)
4. Airway clearance (Vest, Acapella, Flutter, Manual Chest Physiotherapy)
5. Asthma Controller Medications (Flovent®, Advair, Symbicort)
6. Aerosolized antibiotic (Cayston®, TOBI®, Colistin)

If you are taking inhaled corticosteroids or cromolyn/nedocromil sodium you should take those
medicines after you have taken your TOBI ≤. TOBI ≤ should not be mixed with any other
medicine. This repeated pattern of 28 days on and 28 days off will continue until your doctor
tells you otherwise.

Will I need special equipment?
TOBI ≤ comes as a liquid and needs to be made into a mist so that it can go deep into the lungs.
Certain nebulizers must be used in order for TOBI ≤ to be delivered properly. The Pari LC Plus ≤,
or the side stream nebulizer, is used with TOBI ≤. (The Duraneb ≤, which runs on batteries, or any
other portable battery-operated nebulizer, is not powerful enough to create the proper mist.)

How do I use TOBI ≤?
ξ Before beginning the treatment, wash your hands with soap and warm water, or use
anti-bacterial hand gel, to reduce the risk of infection.
ξ Place one vial of TOBI ≤ in the nebulizer cup and throw the empty vial away.
ξ Use a mouthpiece. If you have trouble breathing through your mouth, use nose clips
during the treatments. If you still cannot use a mouthpiece, a mask can be used.
ξ Take a slow deep breath. Every few breaths hold your breath for 5 seconds.
ξ If you have to cough, rest or are interrupted during the treatment, turn the air
compressor off to save your medicine.
ξ The treatment will take between 15-30 minutes.
ξ After the treatment is over, pour 2 teaspoons of clean water into your nebulizer.
Turn the air compressor on and let the water mist through the nebulizer for 15
seconds just as if you were doing a treatment. This will clean out any remaining
TOBI ≤ from the tiny tubes which form the mist.

How Do I Clean and Disinfect My Nebulizer?

Daily cleaning and disinfecting of your TOBI ≤ nebulizer is extremely important in
preventing infection and keeping the nebulizer working well.

Dishwasher Cleaning
1. Take the nebulizer apart.
2. Place the pieces in a dishwasher basket on the top rack of the dishwasher.
3. After the dishwasher cycle is done, remove the pieces and shake out the extra water.
4. Air-dry the nebulizer pieces on a dry paper towel.

Hand Cleaning
If you would prefer not to clean and disinfect your nebulizer using the dishwasher, select one of
the choices below.

Rubbing Alcohol
1. Take the nebulizer apart and wash the pieces in warm soapy water.
2. Rinse with hot tap water.
3. Place the nebulizer pieces in a bowl and add enough rubbing alcohol (isopropyl alcohol)
to completely cover the equipment.
4. Soak the nebulizer for 5 minutes.
5. Rinse all of the parts of the nebulizer with sterile water. Do not use water from the

faucet, bottled, or distilled water, it may be contaminated with germs. You can make
water sterile by boiling it for 5 minutes. Use this water once, and then throw it out.
6. Place the pieces on a paper towel to dry.

1. Take the nebulizer apart and wash the pieces in warm soapy water.
2. Rinse with hot water.
3. Place nebulizer pieces in a bowl, add water to cover.
4. Microwave for 5 minutes.
5. Air dry on a clean paper towel.

If you have questions or need more supplies, contact your Home Health Equipment provider.

Your health care team may have given you this information as part of your care. If so, please use it and call if you
have any questions. If this information was not given to you as part of your care, please check with your doctor. This
is not medical advice. This is not to be used for diagnosis or treatment of any medical condition. Because each
person’s health needs are different, you should talk with your doctor or others on your health care team when using
this information. If you have an emergency, please call 911. Copyright © 3/2017 University of Wisconsin Hospitals
and Clinics Authority. All rights reserved. Produced by the Department of Nursing. HF#5305