Statins (oral) – Pediatrics
Types of statins that are approved for use in children: atorvastatin (Lipitor® or generic), pravastatin
(Pravachol® or generic), rosuvastatin (Crestor® or generic),lovastatin (Mevacor® or generic), extended-release
lovastatin (Altocor®), simvastatin (Zocor® or generic), fluvastatin (Lescol® or Lescol XL® or generic).
Your child has been prescribed _________________________________________.
About Your Child’s Medicine:
ξ Statins are used to decrease LDL (bad)
cholesterol levels in the blood.
ξ Statins stop the liver from making
cholesterol. They also help remove LDL
from the blood and protect the lining of
ξ They may also lower triglycerides and
slightly increase HDL (good) cholesterol
ξ Statins have been shown to reduce the risk
of early cardiovascular disease in adults,
such as heart attacks and strokes.
Before Using This Medicine:
Always tell your child’s provider if your child:
ξ Is allergic to any medicines.
ξ Is taking any other medicines, either
prescription or nonprescription.
ξ Is taking any vitamins and dietary
ξ Has any other medical problems, including
ξ May be pregnant.
How to Use This Medicine:
ξ Remember: These medicines are not a
substitute for a heart healthy diet and
exercise! They are only half as effective if
you eat a diet high in saturated fat (red meat,
fried foods, butter, whole milk, cheese, oils
that are solid at room temperature).
ξ Follow the provider’s instructions for when
to take this medicine. Some statins are more
effective when taken before bedtime while
others should be taken with a meal.
ξ Treatment is usually long-term. When the
cholesterol reaches a healthy level, your child still
needs to take the medicine. If the medicine is
stopped, the cholesterol level will rise again.
ξ Your child’s provider will start with the lowest
dose that will likely lower your child’s LDL to
their goal level. If the cholesterol level is not
lowered enough, the dose may be slowly
ξ Grapefruit and grapefruit juice may interact with
statins. Talk to your child’s provider about these
medicines and eating or drinking grapefruit
Possible Side Effects:
Statins are usually very well tolerated. Side effects
are very, very rare in children. Our concern is that
rarely, liver enzymes (AST, ALT) will increase.
We check liver enzymes when your child’s
cholesterol panel is checked. If your child has any
of these symptoms, report them to your child’s
health care provider:
ξ Sore or weak muscles (severe pain all over the
ξ Abdominal pain
ξ You will need a urine pregnancy test before
starting a statin if you have started to
menstruate (have periods).
ξ Stop the statin right away if you are pregnant or
plan to become pregnant. Taking a statin while
pregnant could harm the unborn baby.
ξ If you are sexually active, you must use a form
of contraception (birth control) while taking a
ξ Use of statins by breastfeeding mothers is not
ξ Fasting blood tests are needed 6-8 weeks after
starting the medicine to see if the statin is
lowering the cholesterol to the goal level.
ξ Once your child has reached the goal
cholesterol level, blood tests are done twice a
year to check cholesterol levels and liver
function until your child is 18 years old.
Your health care team may have given you this information as part of your care. If so, please use it and call if you
have any questions. If this information was not given to you as part of your care, please check with your doctor. This
is not medical advice. This is not to be used for diagnosis or treatment of any medical condition. Because each
person’s health needs are different, you should talk with your doctor or others on your health care team when using
this information. If you have an emergency, please call 911. Copyright © 9/2016 University of Wisconsin Hospitals
and Clinics Authority. All rights reserved. Produced by the Department of Nursing. HF#7924