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How to Give Pancreatic Enzymes to an Infant (6128)

How to Give Pancreatic Enzymes to an Infant (6128) - Clinical Hub, Patient Education, Health and Nutrition Facts For You, Pediatrics, Parenting


How to Give Pancreatic Enzymes to an Infant

1. Open the enzyme capsule and place the
beads in a small dish. Add a small
amount of baby applesauce to the beads.
Mix well. Use the smallest amount of
applesauce needed to mix the beads, as
your baby will have to finish all of the
mixture in order to receive all of the
medicine. You may choose any baby
fruit that is acidic. (Bananas are not
preferred.) The acidity allows for the
mixture to remain stable so the enzymes
do not begin to breakdown.

2. You may notice your baby pushes the
enzymes out of his mouth with his
tongue. That is a normal reflex and will
soon disappear. Spoon in the enzymes
and soon your baby will accept them on
the first try.

3. Once all of the enzymes are gone, give
your baby one spoonful of plain
applesauce to help clean out any leftover
beads. Do a quick finger sweep along
the gum line to remove any leftover
beads. Check your baby’s mouth and
gums to make sure there are no beads
left. If not removed, the beads may
begin to break down and may cause
mouth sores. This is especially
important if your baby is breastfeeding.

4. Give enzymes just before feeding. The
enzymes are effective for about 30
minutes. If a feeding lasts longer than
30 minutes, you should give another
dose. If you give the enzymes and your
baby does not take as much as usual
from the breast or bottle that is fine. If
this becomes a pattern, let the CF Center
know and your baby’s dose may be
changed. You may also choose to give
half of the dose before the feeding and
the rest half way through the feeding.

5. Please do not change the enzyme dose
without talking to the CF Center.

6. Only use brand name enzymes. No
generics should be used.

Common Responses

You may soon notice your baby will have
less gas, a decrease in the number of stools
per day, and less greasy stools. You may
also notice your baby seems more satisfied
after a feeding.

If you notice your baby is having an
increased number of stools, more gas, or
more greasy stools these are signs of
malabsorption. Contact the CF Center and
the enzyme dose may be increased.

If you notice enzyme beads in your baby’s
diaper, that is normal. This often resolves in
the first few weeks. It is most likely due to
an immature gastrointestinal system. It
could be that the coating on the beads is not
being broken down completely in the small
intestine and some of the enzymes are
passing through with undigested food. Do
not worry. Your baby is getting most of the

enzymes. If this continues beyond the first
few weeks, call the CF Center and the dose
may be changed.

If you notice enzyme beads in your baby’s
diaper, use generous amounts of diaper
cream to prevent skin breakdown on your
baby’s bottom.
For questions or concerns, call the CF
Center at 608-263-6420.

If you live out of the area, call 1-800-323-
8942 and ask for the CF Center.

The Spanish version of this Health Facts for You is #7605.

Your health care team may have given you this information as part of your care. If so, please use it and call if you
have any questions. If this information was not given to you as part of your care, please check with your doctor. This
is not medical advice. This is not to be used for diagnosis or treatment of any medical condition. Because each
person’s health needs are different, you should talk with your doctor or others on your health care team when using
this information. If you have an emergency, please call 911. Copyright 3/2017. University of Wisconsin Hospitals
and Clinics Authority. All rights reserved. Produced by the Department of Nursing HF#6128