Amniotic Membrane Graft Surgery
The human amniotic membrane (AM) is the innermost layer of the placenta. The
placenta is tissue that lines the uterus during pregnancy. Due to a number of its
properties, AM is used often in the treatment of severe ocular surface diseases. AM
is made from a fresh placenta under sterile conditions, and washed with a solution
of antibiotics. Testing is done to make sure that each tissue is safe for use in
humans. Amniotic membrane makes anti-inflammatory and growth factors that
help treat the inflammatory diseases of the surface of the eye. AM is secured to the
ocular surface by tissue glue, stitches or an overlying bandage soft contact lens.
Most of the time, the procedure is done in the office setting with an anesthetic.
After application of the amniotic membrane (AMT) on to the eye surface, AM will
be slowly absorbed within 4-6 weeks. Since AM is not a completely transparent
tissue, the patient’s visual acuity may decrease after AMT. The patient should be
aware of this temporary effect before the procedure.
Any surgery prescriptions that you will need will be faxed to your local pharmacy.
Caring for Yourself after Surgery
1. Do not rub your eye or try to clean material from the eye.
2. You may be asked to wear the metal eye shield at night and when napping to
protect the eye. If you wear glasses, wear them during the day. If not, wear the
metal shield. You need to wear the shield for one week. Wearing dark glasses
may help the eye feel more comfortable.
3. Avoid strenuous activity and heavy lifting (over 20 pounds) until cleared by
your doctor. Exercise (i.e. walking) will not harm the eye if done in
moderation. Go slowly and do not strain the first week. Depth perception is
impaired while wearing an eye patch. Be careful on stairs. Do not drive until
cleared by your doctor. Sexual activities may be resumed as soon as you are
4. You may have dull pain, aching, or a scratching feeling in your eye. You may
take acetaminophen (Tylenol®) for relief. If your pain is not controlled by these
medicines, call your doctor.
5. Have your eye drop prescriptions filled and start using them either when you
get home or the next day as you have been instructed.
6. You may shower or bathe as usual. Be careful not to get soap into your eyes.
7. Watching TV or reading will not harm the eye. You may do so if you wish.
Call your doctor right away if you have
An increase in swelling or redness
Any increase in pain or discharge from the eye
A decrease in vision
Nausea or vomiting
University Station Eye Clinic, 8 a.m. to 4:30 p.m., Monday through Friday
When the clinic is closed, your call will be forwarded to the hospital paging
operator. Ask for the “Eye Resident on Call”. Give the operator your name and
phone number with area code. The doctor will call you back.
If you live out of the area, call 1-800-323-8942 and ask to be transferred to the
Please call if you have any questions or concerns.
Your health care team may have given you this information as part of your care. If so, please use it and call if you
have any questions. If this information was not given to you as part of your care, please check with your doctor. This
is not medical advice. This is not to be used for diagnosis or treatment of any medical condition. Because each
person’s health needs are different, you should talk with your doctor or others on your health care team when using
this information. If you have an emergency, please call 911. Copyright © 1/2016 University of Wisconsin Hospital and
Clinics Authority. All rights reserved. Produced by the Department of Nursing. HF#7316