Clinical Hub,Patient Education,Health and Nutrition Facts For You,Nutrition

Food-Drug Interaction: (MAOI) Low Tyramine Diet (154)

Food-Drug Interaction: (MAOI) Low Tyramine Diet (154) - Clinical Hub, Patient Education, Health and Nutrition Facts For You, Nutrition


Low Tyramine Diet

A low tyramine diet is recommended if you are taking certain medicines such as monoamine
oxidase inhibitors (MAOIs), some medicines used to treat Parkinson’s disease, and certain
antibiotics. Tyramine is found mainly in foods that are fermented, aged, or spoiled. Eating
foods that are high in tyramine while taking these medicines can cause side effects such as high
blood pressure, headache, heart palpitations, nausea, vomiting, visual disturbances, and

Some of the drugs that require a low tyramine diet include:

ξ isocarboxazid (Marplan )
ξ linezolid (Zyvox®)
ξ pargyline hydrochloride (Eutonyl )
ξ phenelzine sulfate (Nardil )
ξ procarbazine hydrochloride (Matulane )
ξ tranylcyromine sulfate (Parnate )

Low Tyramine Diet Guidelines include:

ξ You should follow the low tyramine diet while taking the medicine and for 2 weeks after
stopping the medicine.
ξ Fresh foods should be stored at the proper temperatures and cooked or frozen within 24
hours of purchase.
ξ Do not eat cooked foods that are stored in the refrigerator for more than 24-48 hours.
ξ Do not eat foods that are at or beyond their expiration date.
ξ Coffee, cola, and other caffeinated drinks should be limited to a total of 16 ounces per

Food Group Foods Recommended Foods to Avoid
Vegetables ξ All fresh, frozen, or canned
ξ Fermented vegetables such as
sauerkraut and kimchi.
ξ Fermented, decomposed, or
spoiled vegetables.
ξ Chinese pea pods.
ξ Italian broad beans (fava beans).
ξ Fermented soy bean products
(soy sauce, teriyaki, fermented
tofu, miso, tamari, natto, shoyu,
tempeh, and soybean paste).


Food Group Foods Recommended Foods to Avoid
Meats and other
protein sources

ξ All fresh or frozen meats, fish, or
ξ Eggs
ξ Legumes
ξ Nuts
ξ Peanut butter
ξ Fermented meat products such as
chorizo, salchichon, and other
fermented sausages; corned beef.
ξ Dried sausages such as pepperoni,
summer sausage, salami, pastrami,
and mortadella.
ξ Meat products near or beyond the
expiration date.
ξ Chicken and beef liver, pate.
ξ Caviar.
Breads, Grains
and Cereals

ξ Whole wheat and enriched white
breads, rolls, crackers, and quick
ξ Cooked and dry cereals
ξ Grits, pasta and rice
ξ None

ξ Fresh, frozen, or canned fruits and
ξ Banana peels.
ξ Overripe fruits.
ξ Fermented, decomposed, or
spoiled fruit.

Dairy and

ξ Milk
ξ Yogurt,
ξ Fresh cheese such as cottage
cheese or ricotta cheese
ξ Processed cheese made from
pasteurized milk, such as
American cheese and cream
ξ All aged and fermented cheeses
and spreads such as bleu, cheddar,
gouda, muenster, fetabrick, brie,
camembert, cheddar, emmentaler,
gruyere, mozzarella, parmesan,
provolone, parmesan, roquefort,
stilton, and liederkranz.
ξ Any foods containing these
cheeses such as pizza, casserole,
salad dressings, quiche.

ξ Cream and broth based soups,
except those on the Avoid list
ξ Soups made with vegetables on the
Avoid list.
ξ Cheese soup
ξ Soup made with beer or wine

ξ Decaf coffee and tea
ξ Milk
ξ Carbonated drinks
ξ Juices
ξ Non-cola drinks (7-Up , Sprite )
ξ Beer
ξ Wine
ξ Champagne.

Other foods ξ Marmite spread(vegetable
ξ Yeast extracts (Vegemite spread)
ξ All aged products.


Teach Back:

For which medication are you taking that you need to follow a low tyramine diet?

What changes will you make in your diet/lifestyle, based on what you learned today?

If you are a UW Health patient and have more questions please contact UW Health at one of the
phone numbers listed below. You can also visit our website at www.uwhealth.org/nutrition.

Nutrition clinics for UW Hospital and Clinics (UWHC) and American Family Children’s
Hospital (AFCH) can be reached at: (608) 890-5500.

Nutrition clinics for UW Medical Foundation (UWMF) can be reached at: (608) 287-2770.

Your health care team may have given you this information as part of your care. If so, please use it and call if you
have any questions. If this information was not given to you as part of your care, please check with your doctor. This
is not medical advice. This is not to be used for diagnosis or treatment of any medical condition. Because each
person’s health needs are different, you should talk with your doctor or others on your health care team when using
this information. If you have an emergency, please call 911. Copyright © 2/2016 University of Wisconsin Hospitals
and Clinics Authority. All rights reserved. Produced by the Clinical Nutrition Services Department and the Department
of Nursing. HF#154