Clinical Hub,Patient Education,Health and Nutrition Facts For You,Medication Instructions

Ixazomib (Ninlaro) (7941)

Ixazomib (Ninlaro) (7941) - Clinical Hub, Patient Education, Health and Nutrition Facts For You, Medication Instructions


Ixazomib (Ninlaro)

This handout explains what Ixazomib (Ninlaro) is and how it is used.

What is this medicine used for?
ξ To treat transplant organ rejection
ξ To decrease antibodies prior to organ

What do I need to tell my doctor
BEFORE I take this medicine?
ξ Tell your doctor if you are taking
any of these medicines:
Carbamazepine, phenytoin, rifampin,
or St. John's wort.
ξ Tell your doctor if you are
breastfeeding. Do not breastfeed
while you take this medicine.

This is not a list of all medicines that
interact with this Ixazomib. Tell your doctor
and pharmacist about all of your medicines
(prescription or OTC, natural products,
vitamins) and health problems. You must
check to make sure that it is safe for you to
take this drug with all of your drugs and
health problems. Check with your doctor
before you start, stop, or change the dose of
any medicine.

What are some things I need to know or
do while I take this drug?
ξ Tell all of your health care providers
that you take this drug. This includes
your doctors, nurses, pharmacists,
and dentists.
ξ Have blood work checked as you are
told by the doctor.
ξ If your skin touches a broken
capsule, or the drug inside the
capsule, wash the area with soap and
ξ If a broken capsule or the drug inside
the capsule touches your eyes, rinse
your eyes right away with water.
ξ It is not safe to take this medicine
during pregnancy. It could harm an
unborn baby. Tell your doctor right
away if you become pregnant. Both
men and women should use effective
birth control during treatment and for
90 days after the final dose to
prevent pregnancy.

What are some side effects that I need to
call my doctor about right away?
ξ Signs of an allergic reaction:
o Rash
o Hives
o Itching
o Red, swollen, blistered, or
peeling skin with or without
o Wheezing
o Tightness in the chest or throat
o Trouble breathing or talking
o Unusual hoarseness
o Swelling of the mouth, face, lips,
tongue, or throat
ξ Signs of bleeding:
o Throwing up blood or throw up
that looks like coffee grounds
o Coughing up blood

o Blood in the urine
o Black, red, or tarry stools
o Bleeding from the gums
o Vaginal bleeding that is not
o Bruises without a reason or that
get bigger
o Any bleeding that is very bad or
that you cannot stop
o Be careful and avoid injury. Use
a soft toothbrush and an electric

ξ Signs of liver problems:
o Dark urine
o Feeling tired
o Lack of appetite
o Upset stomach or stomach pain
o Light-colored stools
o Throwing up
o Yellow skin or eyes
ξ Other side effects:
o A burning, numbness, or tingling
feeling that is not normal
o Weakness
o Swelling in the arms or legs
o Weight gain
o Nose or throat irritation
o Change in eyesight, eye pain, or
very bad eye irritation
o Loose stools (diarrhea)
o Hard stools (constipation)
o Upset stomach or throwing up
o Back pain

How is this medicine best taken?
ξ Take this medicine as you have been
told by your doctor. Do not use more
than you were told to use.
ξ This medicine is not taken every day.
Be sure you know how to take it.
Talk with your doctor if you have
ξ Take at the same time of day.
ξ Take on an empty stomach at least 1
hour before or 2 hours after meals
unless your doctor has told you
ξ Swallow whole with a drink of
ξ Do not chew, crush, or open the
ξ If you throw up after taking a dose,
do not repeat the dose. Take your
next dose at your normal time.

What do I do if I miss a dose?
ξ Take a missed dose as soon as you
think about it.
ξ If it is less than 3 days (72 hours)
until your next dose, skip the missed
dose. Take your next dose on your
normal day.
ξ Do not take 2 doses at the same time
or extra doses.
ξ Contact your transplant coordinator
if you take your dose more than 3
days late.

Your health care team may have given you this information as part of your care. If so, please use it and call if you
have any questions. If this information was not given to you as part of your care, please check with your doctor. This
is not medical advice. This is not to be used for diagnosis or treatment of any medical condition. Because each
person’s health needs are different, you should talk with your doctor or others on your health care team when using
this information. If you have an emergency, please call 911. Copyright ©11/2016. University of Wisconsin Hospitals
and Clinics Authority. All rights reserved. Produced by the Department of Nursing. HF#7941.

My Ixazomib Schedule:
Please use the following calendar to fill in your ixazomib and dexamethasone schedule. Please
note that after cycle 4 (week 16) you will no longer be taking dexamethasone.

Month 1:
Sunday Monday Tuesday Wednesday Thursday Friday Saturday

Month 2:
Sunday Monday Tuesday Wednesday Thursday Friday Saturday

Month 3:
Sunday Monday Tuesday Wednesday Thursday Friday Saturday

Month 4:
Sunday Monday Tuesday Wednesday Thursday Friday Saturday

Month 5:
Sunday Monday Tuesday Wednesday Thursday Friday Saturday