Clinical Hub,Patient Education,Health and Nutrition Facts For You,Cancer, BMT, Hematology

Sorafenib for the Treatment of Cancer (6676)

Sorafenib for the Treatment of Cancer (6676) - Clinical Hub, Patient Education, Health and Nutrition Facts For You, Cancer, BMT, Hematology


For the Treatment of Cancer

Sorafenib is an oral chemotherapy medicine
given to treat cancer. It is a “targeted agent”
that reduces the blood supply of the tumor
and slows tumor growth.

How It Is Given
Sorafenib is a pill taken twice daily either 1
hour before or 2 hours after eating.

Common Side Effects
 Hand and foot skin reaction –
redness, pain, swelling, or blisters of
the palms of the hands and soles of
the feet. This usually starts 5-6
weeks after starting treatment.These
symptoms may require lowering the
dose of the medication.
 Rash, redness, or itching of skin
 Acne
 Frequent or loose bowel movements
 Loss of appetite
 Nausea
 Fatigue
 High blood pressure especially in the
first six weeks of treatment

Less Common Side Effects
 Heart problems
 Bleeding problems – sorafenib may
increase your risk of bleeding
 Hair thinning
 Mouth sores and dryness
 Weakness
 Swelling in legs
 Allergic reaction-symptoms include:
hives, difficulty breathing, and
swelling of your face, lips, tongue or
throat. If these occur, get emergency

When to Call Your Health Care Provider
 Severe or constant diarrhea, nausea,
vomiting not controlled by medicine
 Bleeding
 Chest pain or shortness of breath
 Fatigue so severe you cannot do your
normal daily routine

Special Concerns
Sorafenib can interact with other medicines
and cause serious side effects. Make sure
that your cancer doctor knows all the
medicines you are taking, prescribed and
over-the-counter, as well as any herbal
supplements. Be sure to tell your cancer
doctor if you are taking the blood thinner
warfarin (Coumadin®).

Your health care team may have given you this information as part of your care. If so, please use it and call if you
have any questions. If this information was not given to you as part of your care, please check with your doctor. This
is not medical advice. This is not to be used for diagnosis or treatment of any medical condition. Because each
person’s health needs are different, you should talk with your doctor or others on your health care team when using
this information. If you have an emergency, please call 911. Copyright © 7/2017. University of Wisconsin Hospitals
and Clinics Authority. All rights reserved. Produced by the Department of Nursing. HF#6676