For the Treatment of Cancer
This is a monoclonal antibody which is a
protein that inhibits (slows) the growth of
new blood vessels. Tumors need to build
blood vessels to grow.
How It Is given
The first IV (intravenous) dose is given over
90 minutes. The second dose is given over
60 minutes. The rest of the doses are given
over 30 minutes. Doses are given every 2
weeks. Blood and sometimes urine will
need to be checked on a routine basis.
Common side effects
• Increased blood pressure during and/or
• Decreased appetite related to dry mouth
• Changes in taste
• Constipation or diarrhea
• Decreased ability for wounds to heal
• Nose bleeds
Uncommon side effects
• Kidney changes --Your doctor will
check lab tests and possibly a urinalysis.
• Allergic reaction.
• Abdominal pain
Call Your Health Care Provider if You
• Coughing blood, nosebleeds which you
cannot stop, blood in stool, urine or
• Abdominal pain
• A change in your blood pressure.
• Headache unrelieved by acetaminophen
• Pain, tenderness, and/or swelling in your
• New or worsening shortness of breath
• Symptoms of an allergic reaction such
o Itching or hives
o New or increased problems breathing
▪ This drug will slow wound healing. You
should avoid any surgery during
treatment and for 28 days once treatment
is completed. This includes placement
of an Infusaport.
▪ You must take proper precautions to
prevent pregnancy for yourself or any
sexual partners during treatment and for
a period of time once treatment is
Adapted, with permission, from the Genentech
Your health care team may have given you this
information as part of your care. If so, please use it
and call if you have any questions. If this information
was not given to you as part of your care, please
check with your doctor. This is not medical advice.
This is not to be used for diagnosis or treatment of
any medical condition. Because each person’s health
needs are different, you should talk with your doctor
or others on your health care team when using this
information. If you have an emergency, please call
911. Copyright © 7/2017. University of Wisconsin
Hospitals and Clinics Authority. All rights reserved.
Produced by the Department of Nursing. HF#6001